Speakers

A FOCUS ON BIOPHYSICS IN CANADA
The BSC 2021 Meeting aims to present a wide range of topics within the field of biophysics from Canadian and international speakers.

2020 NATIONAL LECTURER

DR. JOHN RUBINSTEIN

Professor, University of Toronto

John Rubinstein obtained his B.Sc from the University of Guelph in 1998. He received his PhD from Cambridge University (2002) where he worked in Medical Research Council laboratories under the supervision of Sir John E. Walker and Dr. Richard Henderson. Dr. Rubinstein was a Postdoctoral Research Associate at the MRC Laboratory of Molecular Biology before returning to Canada for a National Cancer Institute of Canada (NCIC) postdoctoral fellowship at the Banting and Best Department of Medical Research. He joined the Research Institute of The Hospital for Sick Children in 2006 and is a Professor in the Departments of Biochemistry and Medical Biophysics.

Dr. Rubinstein’s group, consisting of biophysicists and biochemists, studies the structure and function of macromolecular assemblies using electron cryomicroscopy (cryo-EM), image analysis, molecular biology and molecular genetics. His group also develops the tools of cryo-EM so that they can answer questions that are not amenable to the techniques that currently exist. This process usually occurs at the level of developing new algorithms and software for image analysis and performing calculations with images and models of molecular structure.

Recent biological projects have included the structural study of the mitochondrial ATP synthase, the Vacuolar-type ATPase, and the V/A-ATPase. They also study bacterial toxins that interact with mammalian cells.

2021 YOUNG INVESTIGATOR AWARD

DR. DAVID SIVAK

Associate Professor, Simon Fraser University

David Sivak’s transformative and interdisciplinary research focuses on the field of nonequilibrium statistical biophysics. His recent work touches on the way fluctuation-dominated biomolecular machines operate and how they can achieve efficient energy transduction These fundamentally nonequilibrium questions are of course extremely complex and require novel ways of thinking and novel theoretical tools. Compared to that of many in the field, his work stands out because it is strongly focused on bridging the gap between theory and experiments, by guiding the design of experiments to explore or manipulate molecular systems. His work opens a way to a full understanding of the inner working of molecular machines, and might also bring answers to fundamental questions about the evolutionary optimization of biomolecule structure and function. Perhaps most exciting of all, it might provide guidance for the design of new bio-inspired synthetic machines.

2020 YOUNG INVESTIGATOR AWARD

DR. SABRINA LESLIE

Associate Professor, McGill University

The overarching theme of Sabrina Leslie’s research program is direct visualization of macromolecular dynamics and interactions to understand how living systems work, with key applications in i) diagnostics, ii) pharmaceuticals and iii) nanomaterials.

In particular, the Leslie Lab investigates the fascinating behaviour of macromolecules in squeezed, crowded, and complex environments; conditions which reflect the biochemistry inside living cells. This is an essential aspect of cellular biochemistry that often gets overlooked in the transition from in vitro to in vivo research: that is, understanding the molecular behaviour of biomolecules in context.

KEYNOTE SPEAKERS
Albert Stolow
University of Ottawa (ON)
Catherine Royer
Rensselaer Polytechnic Institute (NY)
INVITED SPEAKERS
Andreas Hilfinger
UofT Mississauga (ON)
Chris Xu
Cornell University (NY)
Isaac Li
UBC Okanagan (BC)
Joanne Lemieux
University of Alberta (AB)
Katherine Borden
Université de Montréal (QC)
Laurent Kreplak
Dalhousie University (NS)
Rikard Blunck
Université de Montréal (QC)
Ruud Veldhuizen
Western University (ON)
Sarah Rauscher
UofT Mississauga (ON)
Sharon Rozovsky
University of Delaware (DE)
Styliani Constas
Western University (ON)
Tanya Dahms
University of Regina (SK)
Valerică Raicu
University of Wisconsin-Milwaukee (WI)
Vincent Tabard-Cossa
University of Ottawa (on)